Cebra

Cebra

CEBRA is a machine-learning method that can be used to compress time series in a way that reveals otherwise hidden structures in the variability of the data.

AppCritica Score 3.6/5

What is Cebra?

Cebra compresses time series to reveal hidden structures in data variability. It excels on behavioural and neural data recorded simultaneously. The method jointly uses behavioural and neural data in a supervised hypothesis-driven or self-supervised discovery-driven manner to produce consistent and high-performance latent spaces. These latents uncover meaningful differences and support decoding tasks. Cebra handles calcium and electrophysiology datasets across sensory and motor tasks in simple or complex behaviors across species. It works with single and multi-session datasets for hypothesis testing or label-free use. Applications include space mapping, kinematic feature analysis, decoding natural movies from visual cortex, and reconstructing viewed videos from mouse brain activity.

More About Cebra

Core Strengths:

  • Produces consistent embeddings from complex time-series data.
  • Supports self-supervised learning with auxiliary variables.
  • Implements algorithms via a PyTorch-compatible API.
  • Offers a high-level scikit-learn-style interface.
  • Includes multiple demo notebooks for diverse datasets.

Pros & Cons

Pros:

Creates consistent latent spaces across sessions and datasets

Handles high-dimensional calcium and electrophysiology data

Reveals hidden behavioral correlates in neural activity

Supports decoding of natural movies from visual cortex

Open source code available on GitHub

Cons:

Limited to time series data common in neuroscience

Requires simultaneous behavioral and neural recordings for optimal use

Primary validation on biological datasets across specific species

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